The Charnolosome as a Novel Nanothereranostic Biomarker

The Charnolosome as a Novel Nanothereranostic Biomarker: Overcoming Future Challenges in Medicine provides an overview of the charnolosome and its potential as a biomarker of cell injury. Based on the author’s original discovery of the charnoly body in the developing undernourished rat cerebellar Purkinje neurons, this book delves into the potential for utilizing this mitochondria and lysosomal-derived intracellular organelle as a nanotheranostic biomarker to prevent and cure various diseases. The book discusses the cellular, molecular, genetic, and epigenetic mechanisms of charnolosomes and charnolosome-derived nano-vesicles. It also investigates the molecular mechanisms underlying auto-inflammatory, autoimmune, and infectious diseases resulting from their compromised mitochondrial bioenergetics, and the potential use of the charnolosome in preventing and curing such conditions. The Charnolosome as a Novel Nanothereranostic Biomarker provides a basis for further study into the field of mitochondrial nanomedicine, sharing new insights into the charnolosome and its potential for the clinical management of diseases at the transcriptional and translational level. This is an ideal reference for researchers in the area of molecular biology, cell biology, epigenetics, nanomedicine, personalized therapeutics, and related fields. Shares the latest knowledge on the charnolosome and charnolosome-derivd nano-vesicles and their significance at a cellular and molecular levelConsiders the charnolosome in relation to a range of conditions, including neurodegenerative, metabolic and multi-drug resistant systemic diseasesPresents future perspectives of the charnolosome in personalized nanotheranostics