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Research on testosterone is increasing in many senses, however there are still much controversy regarding its physiology and clinical use. The present book intends to address these topics, providing a broad overview about testosterone, since its basic features until the most recent evidences of clinical applicability. Also, specific conditions in which testosterone play a pivotal role are discussed in detail, such as hypogonadism, misuse and abuse, puberty, cardiovascular effects and testosterone therapy. Despite not essential for survival, testosterone represents the essence of male biological function, being the important testicular androgen in men. Low serum testosterone levels are associated with cardiovascular morbidity, metabolic syndrome, type 2 diabetes mellitus, atherosclerosis, osteoporosis, sarcopenia, and mortality. Conversely, increased serum levels of testosterone may lead to deleterious events. In general, there is increasing evidence that serum testosterone is a major biomarker status of men's health in general. Testosterone: From Basic to Clinical Aspects intends to be a reference to all those who look for knowledge regarding this hormone, since from basic issues (including pharmacology and physiology) until clinical aspects (related diseases and supplementation therapy).
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