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Providing the most current information§on the function of human growth hormone (GH) and the consequences of its§deficiency, this practical yet comprehensive text is divided into three§sections. Part one describes the mechanisms of GH secretion and action,§including the physiology of GH and its regulation by sex steroids and thyroid§hormones, the effects of both under nutrition and obesity on GH secretion, and§the metabolic effects of human recombinant GH therapy. The second section§covers diagnostic strategies and tests for GH deficiency in both children and§adults, including MRI of the pituitary. The final section describes the§different etiologies of GH deficiency, from molecular mechanisms and gene§abnormalities to cranial radiation and traumatic brain injury, along with§syndromes related to this deficiency. Presenting underlying mechanisms and§pathologies, as well as diagnostic methods, Growth§Hormone Deficiency will provide the most§up-to-date essential information and evidence on this condition for the§clinical endocrinologist.§
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