Contacto
Como comprar
Entrega
Guia de compras
Biochemistry of Chemical Carcinogenesis
Inglês
132 b
Até 30 dias para devoluções
Os clientes também compraram
/
Capa mole
16.98
€
/
Capa mole
16.98
€
/
Capa mole
23.11
€
/
Capa mole
55.57
€
/
Capa mole
101.91
€
The hepatocarcinogenicity of aflatoxin BI in rats, ducks and rainbow trout has been convincingly demonstrated (1). In contrast, adult mice appear to be resistant to the toxic and carcinogenic effects. Newborn and infant mice are more sensitive to the effects of different hepatocarcinogens (2,3) and also to AFB , which induced hepatomas in newborn C57BL/6 x C3H FI I mice (4). A singl~ dose model of aflatoxin hepatocarcinogenesis was tested in infant C57BL/6 mice. AFBI was administered i.p. on day 7 after birth and the following data were investigated: 1) Changes in the activities of microsomal cytochrome P-450 dependant enzymes and conjugating enzymes in the course of the 20-month-Iong aflatoxin hepa tocarcinogenesis study. At intervals of 6,8,12,18 and 20 months a~ter AFBI administration, the concentrations of cyt P-450 andb and the acti 5 vities of NADPH-, NADH-cyt c reductase, AOH, ADM, EH and GST were deter mined. 2) Effect of continually administered diethyldithiocarbamate on the course of aflatoxin carcinogenesis. MATERIALS AND METHODS Aflatoxin BI was prepared biosynthetically in our laboratory and was checked for purity chromatographically, spectrophotometrically and by NMR.
Sobre o livro
Inglês
Ofereça este livro hoje
É fácil
1 Adicione ao carrinho e escolha Entregar como presente ao finalizar a compra 2 Receberá um vale 3 O livro chegará ao endereço do destinatárioTambém pode estar interessado em
/
Livro de capa dura
187.15
€
/
Capa mole
25.92
€
/
Capa mole
6.72
€
/
Capa mole
11.25
€
Olá! Sou o Libroamiko, o seu conselheiro de livros.
Como posso ajudar?