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Antimicrobial Azole Heterocycles: A Study
1,3,4-oxadiazole: A Scaffold Of Antimicrobial Potential
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Inspite of availability of and accessibility of many antibacterial and antifungal drugs in the market, most of them have fallen prey to the increased resistance of microorganisms. In order to defeat this resistance, resistance mechanisms specificity and bacterial, fungal selectivity should be devised as the main targets for enhanced antibacterial and antifungal activity. To fulfill the ever growing demand, there always exist a need for newer molecules which can be obtained by several sources. As the available compounds are mostly non-heterocyclic, synthetic chemists are now focusing on heterocyclic moieties to evaluate their potential as antibacterial and antifungal drugs. This book focuses on synthesis and antimicrobial evaluation of some 2,5-disubstituted-1,3,4-oxadiazole derivatives and a triazole derivative derived from 3-hydroxy-2-naphthoic acid has been described. The data should be especially useful to students, researchers working in the fields of Synthetic chemistry or anyone else who may be considering to discover the safe, potent drug candidates with lesser side effects.
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