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The field of adhesion GPCR biology has indeed become large enough to require a volume dedicated solely to this field. The contributors to this book have made a courageous effort to address the key concepts of adhesion GPCR biology, including the evolution and biochemistry of adhesion GPCRs; there are extensive discussions on the functional nature of these receptors during development, the immune response and tumourgenesis. Finally, there are chapters dedicated to adhesion GPCR signalling, an area of intense investigation. This volume focuses on the recent advances in adhesion GPCR biology.